Norvir (Ritonavir)

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Product of Turkey
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Manufactured by Abbvie

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Manufactured by Cipla Limited

Brand Choices

Product of Turkey
Prescription Required
Manufactured by Abbvie

Generic Alternatives

Product of India
Prescription Required
Manufactured by Cipla Limited

Buy Norvir (Ritonavir) Online

: Medicine Information
Dr. Shruthi Shridhar

Reviewed by : Dr. Shruthi Shridhar

M.D. Physician, MSc. DFSM, CNCC

Therapeutic Class: Protease Inhibitor

Related Medications: Kaletra (Lopinavir / Ritonavir), Synthivan (Atazanavir / Ritonavir )

Health condition: It is an antiretroviral medication used along with other medications to treat HIV/AIDS. This combination treatment is known as highly active antiretroviral therapy.

Introduction of Norvir:

Norvir is the brand name of the drug ritonavir. It is an antiviral drug that helps prevent the Human Immunodeficiency Virus (HIV) from replicating in your body. Norvir is used along with other antiviral drugs to treat HIV and prevent the possibility of Acquired Immunodeficiency Syndrome (AIDS). There is no known cure for HIV or AIDS.

Uses of Norvir:

Norvir is used to control HIV along with other HIV medications. Ritonavir helps reduce the amount of HIV in your body and prevents constant replication of the virus. This boosts your immune system to work better and fight the virus. The drug also lowers your chance of developing HIV complications like cancer, new infections, and thereby improves your quality of life.

Norvir is not the cure of HIV or AIDS. It helps prevent the spread and growth of HIV in your body. While taking Norvir, you will have to continue other HIV medicines as prescribed, continue using barrier method protection during all kinds of sexual activity, and avoid sharing personal items like needles, syringes, razors, toothbrushes, other items that may have blood or body fluids on them.

Side effects of Norvir:

1. Common side effects due to Norvir may include:

  • Nausea, vomiting
  • Stomach pains
  • Diarrhoea
  • Numbness or tingling in your hands, feet, or around your mouth
  • Fatigue, feeling weak or tired
  • Rashes on your skin
  • Changes in the shape or location of your body fat.

2. Severe side effects of Norvir include light-headed feeling, irregular heartbeats, high blood sugar, increased thirst, increased urination, hunger, fruity breath odour, dry mouth, easy bruising, unusual bleeding from the nose, mouth, vagina, rectum, pinpoint purple or red spots under the skin. Some other signs of liver or pancreas being affected may be seen like loss of appetite, nausea, vomiting, dark urine, upper abdominal pain radiation to your back, jaundice.

3. Norvir affects the immune system which leads to certain side effects that can take weeks or months to appear. If you have any of the following symptoms, consult your physician immediately.

  • Speaking trouble, swallowing trouble
  • Problems with balance or eye movement
  • Weakness
  • Prickly feeling
  • Signs of a new infection which include fever, night sweats, swollen glands, cold sores, wheezing, cough, diarrhoea, weight loss.
  • Sweeling in your neck, throat. An enlarged thyroid gland.
  • Menstrual changes
  • Impotence

4. An allergic reaction to this drug is rare. You may present with hives, skin sores, fast or pounding heartbeats, sweating, breathing difficulty, mouth sores, swelling of your throat or face. There is a possibility of a severe skin reaction which includes sore throat, fever, burning eyes, red or purple skin rash with blistering and peeling of skin, pain around the rashes. If you have any signs of an allergic reaction, then consult your physician right away.

If you experience any of the above symptoms, you need to rush to the nearest hospital immediately.

Precautions of Norvir:

Do not consume this drug if:

  • You are allergic to ritonavir
  • You have diabetes
  • You have a bleeding disorder like haemophilia
  • You have a heart disease like coronary artery disease or a heart rhythm disorder
  • You have a liver disease like hepatitis B, hepatitis C
  • You have pancreatitis
  • You have chronic diarrhoea or malabsorption syndrome
  • You have a renal disease
  • You have Osteonecrosis caused due to either alcohol consumption, corticosteroid use, severe immunosuppression or a higher body mass index
  • You are an obese person
  • You have high blood lipid levels like high cholesterol or high triglycerides
  • You consume alcohol on a daily basis
  • You are using marijuana (cannabis)
  • You are going to undergo a surgery within the next 2 weeks
  • You are planning to undergo a dental treatment
  • You are pregnant or planning to conceive
  • You are breastfeeding

Inform your physician about these variables before you begin taking this drug. Norvir is known to interact with most of these disorders and hence the dosage of the medicine will need to be changed or may need to be stopped.

Interactions of Norvir:

Norvir can interact with a variety of drugs. Do not take this medicine if you are using any of the following medicines:

  • Cobicistat
  • Disulfiram
  • Orlistat
  • Alfuzosin
  • Antiarrhythmics like amiodaron, flecainide, propafenone, quinidine
  • Azole antifungals like voriconazole
  • Some benzodiazepines like triazolam, midazolam
  • Blood thinners like rivaroxaban, warfarin
  • Cisapride
  • Eletriptan
  • Medicines for erectile dysfunction or pulmonary hypertension like sildenafil, avanafil
  • Ergot alkaloids like ergonovine, ergotamine, methylergonovine, dihydroergotamine
  • Lurasidone
  • A few opioid pain medicines like meperidine, fentanyl
  • Pimozide
  • Ranolazine
  • Salmeterol
  • Simeprevir
  • Statins like lovastatin, simvastatin
  • Apalutamide
  • Boceprevir
  • Rifampin
  • St. John’s wort
  • Oral contraceptive pills

Inform your physician about your current medication before you start taking Norvir. Do not take disulfiram and alcohol while you are on ritonavir, as this can cause an alcohol reaction.

Over dosage of Norvir:

Overdose of Norvir can cause symptoms of pancreatitis, liver disease or diabetes mellitus. Some other symptoms include rashes, nausea, light-headedness, loss of consciousness. In case of any of these symptoms, rush to the hospital immediately.

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