Formulation: Tablet

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Generic Equivalent to Emend

Formulation: Tablet



Alternate Brand Name(s) : Emend, Emend 2-Day, Emend 3-Day, Aprelief

Aprepitant blocks the actions of chemicals in the body that trigger nausea and vomiting.

Aprepitant is used together with other medications to prevent nausea and vomiting that may be caused by surgery or cancer chemotherapy.

Aprepitant is given ahead of time and will not treat nausea or vomiting that you already have.


The recommended dose for Day 1: 125 mg orally 1 hour prior to chemotherapy

Day 2 and 3: 80 mg orally in the morning

Duration of therapy: Three days

Preventing nausea and vomiting caused by certain types of cancer medicines (chemotherapy). It is used in combination with other medicines. It is also used to prevent nausea and vomiting after surgery. It may also be used for other conditions as determined by your doctor.

Aprepitant is an antiemetic. It works by blocking certain substances in the brain, which helps to prevent nausea and vomiting.


Follow your doctor's instructions about any restrictions on food, beverages, or activity.


There are no data on the excretion of aprepitant into human milk. Because many drugs are excreted in human milk, because of the potential for serious adverse reactions due to aprepitant in nursing infants, and the potential for tumorigenicity shown for aprepitant in rodent carcinogenicity studies, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Active Ingredient: Aprepitant

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