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Formulation: Capsules

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view generic equivalent to Gengraf

Generic Equivalent to Gengraf

Formulation: Capsules



Alternate Brand Name(s) : Gengraf, Neoral, SandIMMUNE

Gengraf lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader. Cyclosporine is used to prevent organ rejection.


The recommended dose of 2 to 4 mg/kg/day IV infusion once a day over 4 to 6 hours or

1 to 2 mg/kg IV infusion twice a day over 4 to 6 hours or

2 to 4 mg/kg/day as a continuous IV infusion over 24 hours.

Capsules: 8 to 12 mg/kg/day orally in 2 divided doses.

Solution: 8 to 12 mg/kg orally once a day.

Gengraf and cyclosporine (modified) are used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. Cyclosporine (modified) is also used alone or with methotrexate (Rheumatrex) to treat the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints) in patients whose symptoms were not relieved by methotrexate alone.

Preventing the rejection of organ transplants (kidney, liver, and heart). It is used in combination with adrenal corticosteroids. It may also be used to treat chronic rejection in patients previously treated with other immunosuppressive agents. It may also be used for other conditions as determined by your doctor.Cyclosporine is an immunosuppressant. It works by suppressing the immune system. This prevents the body from rejecting transplanted organs.


♦ It may cause dizziness, do not drive a car or operate machinery while taking this medication.

♦ Patient may develop with increased risk of Nephrotoxicity, skin cancer; wear protective clothing during outdoors.

♦ Avoid vaccination during the treatment period. This medication may reduce platelet counts; avoid injury or bruising.

♦ Avoid eating Grapefruit or drinking Grapefruit juice while taking this medication.


A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Yes Excreted into animal milk: Unknown The effects in the nursing infant are unknown.

Due to potential effects in the nursing infant, such as immunosuppression, neutropenia, growth retardation, and possible carcinogenesis, cyclosporine is not recommended during lactation. Cyclosporine use during lactation is considered contraindicated by the American Academy of Pediatrics. Some formulations of cyclosporine contain ethanol. Ethanol will be present in human milk at levels similar to that found in maternal serum and if present in breast milk will be orally absorbed by a nursing infant.

Active Ingredient: Ciclosporin

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